{"href":"https://api.simplecast.com/oembed?url=https%3A%2F%2Famindr.com%2Fepisodes%2F274-vascular-contributions-to-alzheimers-disease-february-2022-wg4kDqsv","width":444,"version":"1.0","type":"rich","title":"274 - Vascular Contributions to Alzheimer's Disease: February 2022","thumbnail_width":300,"thumbnail_url":"https://image.simplecastcdn.com/images/9a8ef428-72db-47cb-a5cb-a6a258a13785/319aef41-afa3-4539-bab6-d7e2109b9f02/slide2-4.jpg","thumbnail_height":300,"provider_url":"https://simplecast.com","provider_name":"Simplecast","html":"<iframe src=\"https://player.simplecast.com/7849756a-7ffb-44b1-a3c6-8aa87694beb8\" height=\"200\" width=\"100%\" title=\"274 - Vascular Contributions to Alzheimer&apos;s Disease: February 2022\" frameborder=\"0\" scrolling=\"no\"></iframe>","height":200,"description":"Ever wondered how amyloid deposited in cerebral vessels might affect cerebrovascular reactivity? Or how the culture time of iPSC-derived brain microvascular endothelial-like cells changes their phenotype? Well, you've come to the right place. Elyn will take you through all this and more as she emphasizes the importance of cerebrovascular health in the context of Alzheimer disease in this episode covering papers published on PubMed in February 2022. \n\nSections in this episode: \nClinical Insights: Neuroimaging and Vascular Risk Factors (3:51) \nPreclinical Insights: Methodology and BBB Regulation (25:47) \nTreatment Avenues (32:19) "}