{"href":"https://api.simplecast.com/oembed?url=https%3A%2F%2Famindr.com%2Fepisodes%2F314-vascular-changes-in-alzheimers-disease-october-2022-hU2Wu_Wu","width":444,"version":"1.0","type":"rich","title":"314 - Vascular Changes in Alzheimer's Disease: October 2022","thumbnail_width":300,"thumbnail_url":"https://image.simplecastcdn.com/images/9a8ef428-72db-47cb-a5cb-a6a258a13785/168b1938-a544-45eb-982f-96b1066bae1f/slide2-1-1.jpg","thumbnail_height":300,"provider_url":"https://simplecast.com","provider_name":"Simplecast","html":"<iframe src=\"https://player.simplecast.com/b6f7eb5b-644f-423c-a835-928314e9084a\" height=\"200\" width=\"100%\" title=\"314 - Vascular Changes in Alzheimer&apos;s Disease: October 2022\" frameborder=\"0\" scrolling=\"no\"></iframe>","height":200,"description":"In this episode, Elyn takes you through 13 papers from October 2022 published on vascular contributions to Alzheimer disease. It's quite the journey through mechanistic mouse studies, neuroimaging studies, and a few studies assessing treatments targeting the vasculature, which all paint a pretty convincing picture of the importance of the cerebrovasculature in brain health. Tune in to learn more about the glymphatic system, consequences of amyloid deposition on the vasculature, and a clinical study testing out albumin replacement as an AD treatment! \n\nSections in this episode: \nVascular Implications of Amyloid Accumulation (3:52) \nGlymphatic System (7:31) \nOther Clinical Studies (10:57) \nCo-morbidities and Risk Factors (15:20) \nTreatment Avenues (22:15) "}