{"href":"https://api.simplecast.com/oembed?url=https%3A%2F%2Fbipedal.simplecast.com%2Fepisodes%2Fplatelet-rich-plasma-vPJWAxhu","width":444,"version":"1.0","type":"rich","title":"Platelet Rich Plasma","thumbnail_width":300,"thumbnail_url":"https://image.simplecastcdn.com/images/a30f2a57-bd36-48e5-8ed6-c77057fa3913/b8d45575-ec7c-410d-82bd-790e12c19ad4/bipedal-20cover-20art.jpg","thumbnail_height":300,"provider_url":"https://simplecast.com","provider_name":"Simplecast","html":"","height":200,"description":"Platelet-rich plasma, or PRP, has become one of the most talked-about treatments in modern sports medicine, orthopedics, and podiatry. But does it actually work? In this first episode of season 3 we take a detailed look at the science behind PRP—from how it is prepared from a patient's own blood to the growth factors and signaling molecules that may influence tissue healing. We explore how PRP is used in orthopedics and foot and ankle medicine, including treatment of knee arthritis, plantar fasciopathy, Achilles tendinopathy, and other tendon and joint conditions.\nBut this episode isn't simply about why PRP might work. We also examine the evidence showing where PRP doesn't appear to provide a meaningful benefit over placebo. You'll learn why two treatments both labeled \"PRP\" can actually be very different biologic products, why platelet concentration and white blood cell content matter, and why a convincing biological mechanism doesn't necessarily translate into better outcomes for patients. Most importantly, we look at what randomized clinical trials and meta-analyses actually tell us about PRP—and how patients should think about the potential benefits, limitations, costs, and alternatives before deciding whether it is right for them.\nPRP isn't magic, but it isn't snake oil either. The truth is considerably more interesting."}