{"href":"https://api.simplecast.com/oembed?url=https%3A%2F%2Fnucleate-signal.simplecast.com%2Fepisodes%2Ffounding-of-biotech-phillip-a-sharp-kOMp_5BS","width":444,"version":"1.0","type":"rich","title":"From Nobel-Winning Discovery to Co-Founding Biogen | Phil Sharp","thumbnail_width":300,"thumbnail_url":"https://image.simplecastcdn.com/images/ed52f7f3-cb55-48af-ae20-82bc5484ef83/39173334-825d-4740-b38d-f4948b1ddd57/cropped_1790221586312.jpg","thumbnail_height":300,"provider_url":"https://simplecast.com","provider_name":"Simplecast","html":"<iframe src=\"https://player.simplecast.com/3ff79fe7-9fb0-499c-ac8c-13043f086e34\" height=\"200\" width=\"100%\" title=\"From Nobel-Winning Discovery to Co-Founding Biogen | Phil Sharp\" frameborder=\"0\" scrolling=\"no\"></iframe>","height":200,"description":"In this episode of the podcast we are joined by Dr. Phillip Sharp, Nobel Prize Laureate and Institute Professor at MIT, who shares his story behind the groundbreaking discovery of RNA splicing. He explains how the work ethic and problem solving instinctions he built early on eventually led him to Caltech, and then MIT, where his 1977 discovery changed how we understand gene expression. \n\nSharp discusses his  journey from science into biotech entrepreneurship, co-founding both Biogen and Alnylam, and delves into his role as a pioneer of the industry. This episode offers a firsthand account of biotech’s earliest days, along with advice for founders on risk, communication strategies, and what it takes to build a successful company. \n\nBook mentioned: \nThe Double Helix by James D. Watson"}