{"href":"https://api.simplecast.com/oembed?url=https%3A%2F%2Four-untangled-minds.simplecast.com%2Fepisodes%2Fs7-e4-car-t-cell-therapy-muNrPT0O","width":444,"version":"1.0","type":"rich","title":"S7: E4 CAR-T Cell Therapy","thumbnail_width":300,"thumbnail_url":"https://image.simplecastcdn.com/images/96c82667-dba7-414a-8201-a41300d9f776/819712e8-c175-44c4-9e28-8ddc5fbccb52/jpg-logo-file.jpg","thumbnail_height":300,"provider_url":"https://simplecast.com","provider_name":"Simplecast","html":"<iframe src=\"https://player.simplecast.com/49b0a505-8bee-4c9d-af44-5c7dced64eee\" height=\"200\" width=\"100%\" title=\"S7: E4 CAR-T Cell Therapy\" frameborder=\"0\" scrolling=\"no\"></iframe>","height":200,"description":"Chimeric antigen receptor (CAR)-T cell therapy has made impressive advancements in treating patients with blood cancers, such as leukemia and lymphoma, for more than a decade now. In this episode, we traverse the challenges and innovations of cell immunotherapy and better understand the design behind these logic-gated, genetically engineered cytotoxic cells with Dr. Yvonne Chen, a leading expert in the field. Dr. Chen is an incredibly accomplished Professor of the MIMG and CBE departments at UCLA and currently leads a Phase 1 Clinical Trial (NCT04007029) using bispecific anti-CD19/anti-CD20 CAR-T cells to treat patients with B cell malignancies. \n For more information on Dr. Chen’s research: http://yvchen.bol.ucla.edu/. \n\nMusic: https://pixabay.com/music/id-112777/ \n\nEpisode Team: \nGuests - Dr. Yvonne Chen\nHost - Brenda Ji\nScript Writers - Brenda Ji\nAudio - Daniel Nguyen\nProducers - Artin Allahverdian, Sonali Joshi \nDirector - Vy Han, MD "}