{"href":"https://api.simplecast.com/oembed?url=https%3A%2F%2Fpods-of-science.simplecast.com%2Fepisodes%2Fhow-to-outsmart-cancer-cells-5RqU4AbB","width":444,"version":"1.0","type":"rich","title":"How to Outsmart Cancer Cells","thumbnail_width":300,"thumbnail_url":"https://image.simplecastcdn.com/images/3f633704-8221-4c4c-88cf-9430a5a1042c/59e62d33-890c-4042-881a-44a1e2cb1ecd/108812871-10223815129430805-8533194097912262996-o.jpg","thumbnail_height":300,"provider_url":"https://simplecast.com","provider_name":"Simplecast","html":"","height":200,"description":"\nA study published in Cell provides an unprecedented look at the dozens of molecular steps that occur to bring about endometrial cancer, commonly known as uterine cancer. The study offers insights about how physicians might be able to better identify which patients will need aggressive treatment and which won’t, and offers clues about why a common treatment is not effective with some patients.\n\nThe study, funded by the National Cancer Institute, also suggests a potential role for already-approved drugs that target proteins known as CDK12, SMARCA4 and PML in other types of cancer.\n\nOne could say that the work is a detailed molecular snapshot of endometrial cancer – except that the information is so vast, touching upon tens of thousands of molecular actors taking part in thousands of interactions at different times, that the work is more like a frame-by-frame video, documenting steps that play out over years in patients’ bodies."}